We design personalized protocols grounded in scientific evidence, with 41 clinical peptides and 15 synergistic stacks. Tissue repair, cellular longevity, metabolism, hormonal axis, and cognitive function — under the direct medical supervision of Dr. Fernando Terán Flores.
A quick primer: what peptides are, how BPC-157 and TB-500 work, and what they resolve when combined. Swipe ➜
Answer 4 questions and our selector recommends the 1–3 protocols that best fit your goal. The final decision is always validated by your FISIUM physician.
4 questions · under 1 minute
Each area activates specific molecular pathways. Our protocols combine peptides with synergistic action to maximize clinical outcomes.
Angiogenesis, collagen remodeling, and accelerated injury recovery.
Secretagogues and GH-RH analogs that restore the physiological GH/IGF-1 axis.
Glycemic control, satiety, and body composition remodeling.
Telomerase activation and mitochondrial biogenesis for healthy aging.
Neuroprotection, anxiety, sleep, and sexual function with Russian peptides and analogs.
Collagen, fibroblasts, and skin pigmentation with copper tripeptides.
Each peptide acts via a specific molecular pathway. Filter by category to explore mechanisms, indications, and the clinical dosing used in our protocols.
Mechanism: upregulates VEGFR2, driving local angiogenesis; activates the nitric oxide (NO) pathway; and induces type I collagen synthesis by fibroblasts. Inhibits NF-κB for an anti-inflammatory effect.
Systemic action: repairs muscle, tendon, ligament, and peripheral nerve. Heals gastric ulcers and protects against NSAID damage. Restores endothelial function.
Mechanism: regulates the G-actin to F-actin polymerization, facilitating cell migration to the injury site. Down-regulates TNF-α and IL-1β; stimulates angiogenesis.
Systemic action: repairs grade II–III muscle injuries, prevents fibrosis, and reduces scar tissue. Cardiomyocyte recovery.
Mechanism: stimulates collagen I, III, and elastin via fibroblasts; up-regulates VEGF (angiogenesis); activates metallothioneins (antioxidant); and modulates TGF-β1.
Systemic action: skin firmness, wound regeneration, follicular stimulation in alopecia, and repair of articular cartilage and scars.
Mechanism: inhibits SNARE complex formation at the facial neuromuscular junction, reducing acetylcholine release (a reversible action similar to botulinum toxin).
Systemic action: relaxes facial expression muscles, softening dynamic wrinkles. Topical or local subcutaneous application with a gradual cosmetic effect.
Mechanism: activates the IGF-1R receptor, triggering the PI3K/Akt/mTOR pathway. Its modification reduces affinity for IGFBPs >1000× and extends half-life to 20–30 h.
Systemic action: muscle hypertrophy and hyperplasia, anti-catabolism in a caloric deficit, post-injury repair, and lean mass preservation in sarcopenia.
Mechanism: IGF-1 analog with the 3 N-terminal amino acids removed. Higher local receptor affinity and lower systemic effect — ideal for focal post-injury action.
Systemic action: localized anabolic effect in the injected muscle and post-workout recovery, with less impact on blood glucose than IGF-1 LR3.
Mechanism: selective ghrelin receptor (GHSR-1a) agonist. Releases endogenous GH without raising cortisol or prolactin — a key difference from GHRP-2 / GHRP-6.
Systemic action: pulsatile increase in GH and IGF-1, protein synthesis, lipolysis without catabolism, and improved deep-sleep quality.
Mechanism: GHRH(1-29) analog with a ~30 min half-life; induces a physiological GH pulse while preserving somatostatin feedback.
Systemic action: increased GH and IGF-1, type I and II collagen synthesis, bone/joint remodeling, and improved nutrient partitioning.
Mechanism: GHRH analog bound to albumin via DAC, half-life ~8 days. Sustains elevated GH and IGF-1 levels continuously.
Systemic action: raises GH/IGF-1 steadily with a single weekly dose, ideal for long-duration protocols with a light injection schedule.
Mechanism: synthetic GHRH analog with extended half-life that stimulates the pituitary to release GH in pulses. The only FDA-approved GHRH.
Systemic action: up to 18% visceral fat reduction, IGF-1 increase, improved body composition and lipid profile, cognitive benefits.
Mechanism: natural analog of the active fragment of human GHRH. Induces physiological GH pulses while fully preserving the hypothalamic-pituitary axis.
Systemic action: gradual GH/IGF-1 increase with a very high safety profile. Indicated for hormonal aging and relative GH deficiency.
Mechanism: recombinant human growth hormone identical to the endogenous form. Acts directly on the liver to produce IGF-1 and drive systemic anabolic effects.
Systemic action: increased lean mass, lipolysis, improved bone density, and recovery. Only under strict clinical supervision and glycemic monitoring.
Mechanism: inhibits myostatin (GDF-8), the natural brake on muscle growth. Blocking it releases anabolic potential via the Smad/follistatin pathways.
Systemic action: muscle growth beyond the genetic ceiling, post-injury recovery, and management of advanced sarcopenia.
Mechanism: mimics LH by binding the LHCGR receptor on Leydig cells, stimulating endogenous testosterone production and preserving testicular function.
Systemic action: HPG-axis recovery in TRT, male fertility, prevention of testicular atrophy. In women, supports ovulation induction.
Mechanism: contains FSH and LH activity. Directly stimulates follicular growth in women and spermatogenesis together with HCG in men.
Systemic action: fertility protocol and gonadal-axis restoration in male infertility secondary to prolonged androgen use.
Mechanism: activates β-3 adrenoceptors in adipose tissue and inhibits de novo lipogenesis. Does not activate IGF-1R, so it lacks the anabolic/diabetogenic effects of full GH.
Systemic action: selective visceral lipolysis without fluid retention or glycemic disruption. Compatible even with diabetic profiles.
Mechanism: selective GLP-1 receptor agonist. Suppresses appetite centrally, slows gastric emptying, and increases glucose-dependent insulin release.
Systemic action: 10–17% weight loss, HbA1c reduction, cardiovascular protection, and improvement of hepatic steatosis (NAFLD).
Mechanism: dual GLP-1R + GIPR agonist. GLP-1 suppresses appetite and slows emptying; GIP potentiates insulin and muscle glucose uptake.
Systemic action: 15–22% weight loss, up to 2.5% HbA1c reduction, better preservation of muscle mass than GLP-1 alone, and improved lipid profile.
Mechanism: triple incretin agonist. Adds glucagon-receptor activation to tirzepatide's action → lipolysis and increased basal energy expenditure.
Systemic action: weight loss up to 24%, intense reduction of triglycerides and hepatic fat, improvement of severe visceral adiposity.
Mechanism: amylin mimetic with central anorexigenic action. Synergizes with semaglutide (CagriSema combination), boosting satiety and weight loss.
Systemic action: additional appetite control in patients with partial GLP-1 response, better long-term weight maintenance.
Mechanism: dual agonist with a preference for the glucagon receptor over GLP-1, profile distinct from tirzepatide. Combines appetite suppression with potent lipolysis.
Systemic action: weight loss with a stronger thermogenic component, hepatic fat reduction, and improved lipid profile.
Mechanism: selectively targets pro-apoptotic action to white adipose tissue vessels via prohibitin/ANXA2, inducing regression of adipocyte vasculature.
Systemic action: rapid fat mass reduction in refractory obesity. Experimental use, requires strict medical monitoring.
Mechanism: the only peptide encoded by the mitochondrial genome. Activates AMPK as a central energy sensor and promotes mitochondrial biogenesis via PGC-1α.
Systemic action: improves insulin sensitivity, muscle fatty-acid oxidation, aerobic capacity, and muscle preservation with aging.
Mechanism: inhibits the enzyme nicotinamide-N-methyltransferase (NNMT) in adipocytes, restoring the NAD+ and SAM pool in fat tissue.
Systemic action: reactivates metabolism in hypertrophic adipocytes, pure lipolysis without affecting muscle mass, an ideal complement to GLP-1 stacks.
Mechanism: essential coenzyme for sirtuins (SIRT1-7), PARP, and mitochondrial redox reactions. Levels fall with age, compromising oxidative phosphorylation.
Systemic action: restores cellular energy, reduces oxidative damage, improves mental clarity, post-exercise recovery, and mitochondrial biogenesis.
Mechanism: binds selectively to cardiolipin in the inner mitochondrial membrane, stabilizing respiratory complexes and reducing ROS without neutralizing endogenous antioxidants.
Systemic action: functional recovery in mitochondriopathies, chronic fatigue, cardiomyopathy, and cognitive decline linked to mitochondrial damage.
Mechanism: the master endogenous antioxidant. Cofactor for glutathione peroxidases and hepatic phase II conjugation; neutralizes ROS and heavy metals.
Systemic action: deep hepatic detoxification, skin protection (mild depigmentation), support for fatty liver, chronic fatigue, and toxic exposure.
Mechanism: agonist of the Estrogen-Related Receptors (ERRα/β/γ). Activates programs of mitochondrial biogenesis and fatty-acid oxidation similar to those triggered by exercise.
Systemic action: improves aerobic capacity, muscle endurance, and metabolic efficiency — useful as an adjuvant in weight loss and rehabilitation.
Mechanism: activates telomerase (hTERT), lengthening telomeres; regulates pineal melatonin production and normalizes circadian rhythm and the HPA axis.
Systemic action: cellular longevity, deep sleep, reduction of chronic oxidative stress, and restoration of neuroendocrine function with age.
Mechanism: peptide complex extracted from bovine thymus. Restores T-lymphocyte maturation and the adaptive immune response that declines with age.
Systemic action: immune rejuvenation, better vaccine response, anti-immunosenescence, and protection against recurrent infections in older adults.
Mechanism: derived from the 4-7 fragment of ACTH + Pro-Gly-Pro. Raises BDNF and NGF release, modulates the dopaminergic/serotonergic systems, neuroprotective in ischemia.
Systemic action: improves memory, executive function, and reaction speed. Reduces mental fatigue, enhances neuroplasticity and sustained focus.
Mechanism: synthetic tuftsin analog. Modulates the GABAergic system (inhibitory transmission), regulates the HPA axis by reducing chronic cortisol, and stimulates BDNF.
Systemic action: anxiolysis without sedation or dependence, improved focus, sleep normalization, and adaptive immune modulation.
Mechanism: melanocortin (MC3R/MC4R) CNS agonist that activates the dopaminergic reward system. Central mechanism — independent of PDE5/mechanical erection.
Systemic action: stimulates sexual desire in men and women, useful for hypoactive sexual desire disorder (HSDD) and neurogenic erectile dysfunction.
Mechanism: non-selective MC1R/MC3R/MC4R/MC5R agonist. MC1R stimulates melanogenesis (eumelanin); MC4R activates libido and reduces appetite.
Systemic action: UV-independent tanning, skin photoprotection, sexual desire stimulation, and moderate appetite suppression.
Mechanism: endogenous nonapeptide that crosses the blood-brain barrier, modulates GH release, and promotes entry into delta (slow-wave) sleep.
Systemic action: improves the quality and architecture of deep sleep, dampens stress, regulates nocturnal blood pressure, and supports physical recovery.
Mechanism: derived from the innate erythropoietin receptor (no erythropoietic effect). Activates the heterodimeric EPOR/βcR receptor with cytoprotective and anti-inflammatory neuronal function.
Systemic action: relief of neuropathic pain, small-fiber neuropathy, and chronic inflammatory processes without stimulating hematopoiesis.
Mechanism: hormone/neuropeptide that acts on central OXTR receptors, modulating trust, emotional bonding, and empathy. Peripherally regulates uterine contraction and milk ejection.
Systemic action: reduction of social anxiety, improved pair bonding, and emotional regulation. Controlled clinical use.
Mechanism: activates the hypothalamic KISS1R receptor, the main driver of the reproductive axis. Stimulates GnRH release and, secondarily, LH/FSH.
Systemic action: HPG-axis restoration, physiological alternative to HCG in post-cycle, gonadal function assessment, and management of functional hypogonadism.
Mechanism: thymic peptide that matures precursor T cells, modulates TLR receptors, and improves adaptive and innate immune response without generating systemic inflammation.
Systemic action: adjunct in hepatitis B/C, post-cancer, chronic infections, sepsis, and immune restoration in immunosenescent patients.
Mechanism: C-terminal tripeptide of α-MSH. Inhibits the NF-κB pathway and reduces pro-inflammatory cytokines (IL-1β, TNF-α) in mucosa, skin, and gut.
Systemic action: mucosal anti-inflammatory (gastritis, IBD, colitis), support for acne/dermatitis, and modulation of cutaneous and digestive immune systems.
Mechanism: endogenous antimicrobial peptide with broad-spectrum activity against bacteria, fungi, and viruses. Also modulates local immune response and wound healing.
Systemic action: resistant skin infections, persistent biofilms, chronic wounds, and innate immunity support in immunocompromised patients.
We combine peptides by mechanistic synergy — no overlap — to cover the entire therapeutic goal in a single protocol. Three levels of complexity: beginner, intermediate, and advanced.
⚡ Most requested
Beginner
Function: accelerated repair of soft and musculoskeletal tissue.
Benefits: recovery from muscle injuries, tendinopathies, and sprains; shorter return-to-activity time; adjunct gastrointestinal protection.
Intermediate
Function: skin rejuvenation, collagen synthesis, and aesthetic tissue repair.
Benefits: skin firmness and elasticity, better post-procedure healing, visible reduction in fine lines, and improved hair quality.
Advanced
Function: maximum anti-inflammatory + tissue repair + skin regeneration.
Benefits: ideal for chronic inflammatory conditions involving skin or mucosa; adds KPV to shut down the immune component.
Beginner
Function: endogenous growth hormone optimization, muscle mass, sleep, and body composition.
Benefits: the most-studied GH duo; physiological nocturnal pulse without altering cortisol or prolactin, deliverable in a single syringe.
Advanced
Function: maximum hypertrophy, advanced sarcopenia, and body recomposition.
Benefits: adds direct anabolism (IGF-1 LR3) to the pituitary stimulus; requires strict glycemic monitoring and short cycles.
Intermediate
Function: visceral fat loss, lipodystrophy, and body recomposition without compromising lean mass.
Benefits: dual GH-axis stimulation (morning and night) for sustained lipolysis; measurable waist reduction and improved lipid profile.
Advanced
Function: extreme body recomposition — simultaneous fat loss and muscle gain.
Benefits: elite protocol for athletes and plateaued patients; combines hormonal lipolysis + direct anabolism under intensive medical supervision.
Intermediate
Function: cellular longevity, telomeres, and hormonal anti-aging.
Benefits: telomerase activation + GH-axis restoration; marked improvement in deep sleep, daytime energy, and body composition in patients over 40.
Intermediate
Function: comprehensive anti-aging — telomeres + mitochondria + collagen + GH.
Benefits: targets 4 hallmarks of aging simultaneously; ideal for long-term maintenance and measurable systemic rejuvenation.
Beginner
Function: cognitive performance, neuroprotection, and stress/anxiety management without sedation.
Benefits: the most-documented nootropic stack; improves focus, memory, and reduces performance anxiety without dependence.
Intermediate
Function: comprehensive women's protocol — skin, sleep, anxiety, and cellular longevity.
Benefits: aesthetic results + emotional wellbeing + skin repair with a twice-yearly Epithalon cycle for continued maintenance.
Advanced
Function: total repair — muscle + tendon + collagen + reparative anabolism.
Benefits: intensive protocol for post-major-surgery or complex injuries; adds IGF-1 LR3 to the base stack to accelerate tissue consolidation.
Function: central sexual desire activation + performance anxiety control.
Benefits: dual pathway — central libidinal (PT-141) + anxiolysis (Selank); useful when low libido and chronic stress coexist.
Function: comprehensive metabolic control — glycemia + weight + mitochondrial energy.
Benefits: three non-overlapping mechanisms (appetite, pure lipolysis, and mitochondrial biogenesis) for sustainable results in metabolic obesity.
Function: high performance — simultaneous accelerated recovery + GH optimization.
Benefits: post-workout recovery + physiological nocturnal GH stimulus; ideal for athletes in-season or during pre-season.
No vague promises. Every step has a medical deliverable and metrics so you know where you are and where you are going.
Complete medical history, focused physical exam, and lab work tailored to the therapeutic goal.
Stack selection and personalized dosing. Training on self-injection technique, vial handling, and reconstitution.
Cycle kickoff with biweekly physician follow-up and a direct support line for questions and adjustments throughout the cycle.
Re-evaluation with objective metrics, maintenance adjustments where applicable, and a secondary-prevention plan.
We work only with pharmaceutical-grade peptides under continuous medical supervision. We do not improvise protocols: we replicate what the international clinical literature validates.
Every batch validated by chromatography. No surprises in composition or contaminants that could compromise results.
A physician stays with you before, during, and after the cycle. Results with no ambiguity — no "personal experimentation."
Av. López Mateos 184-PB, Porto Reale Building (24120). In-person care and telemedicine for ongoing protocols. Supplies, guidance, and follow-up all under one team.
Every protocol is backed by peer-reviewed literature and the accumulated clinical experience of the FISIUM team.
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